For those of you who haven’t been paying attention, Factor4 is fast becoming one of the most talked about treatments of 2016. Some of Australia’s best practitioners and surgeons have also embraced Factor4 – one of the more well-known and respected being Dr Bryan Mendelson and his Skin & Injecting Clinic in Toorak, Victoria. We contacted Dr Mendelson, and his Dermal Clinician Natasha Laouta who has over 20 years of industry experience and is trained to the highest level to administer and assist in non-surgical skin rejuvenation, including medical, aesthetic, cosmetic skin care treatments, as well as the operation of laser and electrical based equipment; to get the lowdown on why everyone is loving the Factor4 treatment and why their unique method of micro-needling combined with the Factor4 treatment is producing superior results.

Natasha Laouta

Natasha Laouta, Dermal Clinician

PSH: What is it about the Factor4 treatment that sets it apart from others?

Factor 4 is a new generation platelet rich plasma (PRP), an autologous anti-ageing serum, highly concentrated and super rich blood serum containing four times more growth factors than any brand blood rich injection product on the market.

PSH: Does the process hurt, and how long does it take?

Each treatment takes approximately an hour and a half. This includes time for the numbing cream to take effect, followed by the skin needling procedure with the Factor4 serum and 13 minute LED therapy which assists with healing.

Due to the numbing cream, patients feel little more than light scratching on their skin. We also gauge the intensity on the client’s comfort levels as some areas of the face are more sensitive than others.

PSH: The results are said to improve over time. What is the recommended number of treatments (we hear 4 – 6 treatments will be needed with 2 or so weeks in between each treatment)? How long do the results last and how often do you need “top ups”?

A minimum of 4 treatments is generally required to achieve the optimum rejuvenation of the area. Recent research has resulted in a recommendation that skin needling treatments should be performed at weekly to fortnightly intervals to achieve the best possible results.

The true result of the treatment will be apparent approximately 3-6 months post treatment as your skin regenerates and continues to produce more collagen and elastin. Top ups are recommended every 6 months or annually depending on the condition and quality of the skin. A maintenance program can also be considered ie. an additional 4 treatments 6 weeks apart.

Dr Mendelson Clinic

Dr Bryan Mendelson’s Skin & Injecting Clinic in Toorak

PSH: Are there any risks associated with the procedure and is it suitable for everyone?

Being an autologous serum it contains no cellular matter, limiting the risk of infection as well as no risk of bacteria or cancerous cell transfer.

Following the treatment a mild inflammatory reaction occurs, resulting in a warm, flushed feeling similar to a moderate sunburn. Skin redness can persist for up to 24 – 48 hours. It is normal for the skin to feel tender and in some instances mild bruising and swelling around the eyes and lips can be noticed.

This treatment is suitable for everyone particularly those with fine lines, dull skin, enlarged pores, acne scars, chicken pox scars and surgical scars, nasolabial fold lines, smoker’s lines and those seeking rejuvenation of hands, neck and decolletage, lax skin on the body – arms, legs and stomach. It is NOT suitable over skin cancer and active acne or during pregnancy.

PSH: It is said the most popular place to have the treatment is on the face, but it is possible to have the treatment almost anywhere on the body. Where do you find you are performing the treatment most and where are you getting the best results for the treatment?

We perform most of our treatment on the face, neck and decolletage and back of hands. The best results we have seen have been the neck, under the eyes, and nasolabial fold. In addition to visible appearance there is a softness of fine lines and pores.

PSH: Talk us through how the actual procedure works and what is happening to our skin in order for the treatment to work as well as it does.

The treatment involves the use of an electrical device called MDerma which uses tiny needles to create micro-injuries to the skin. These micro injuries induce a natural wound healing response which includes the release of growth factors and the deposition of new collagen and elastin to heal the skin. Applying the Factor4 serum over the skin whilst needling means results are enhanced as there is four times the growth factors helping your skin heal, and rejuvenate.

PSH: How can people contact you if they want more information or would like to arrange a consult or treatment?

For further information on Factor4 at the Skin & Injecting Clinic visit or call +61 3 9826 0977.


Trish is a plastic surgery blogger. She is passionate about wellbeing, health and beauty, and doesn't mind a little bit of 'help' from the amazing cosmetic and beauty procedures that are available today. Trish spends her days talking to women and men who are looking for suggestions and advice on procedures that are available to them. Cutting through the sales pitch and hype, a down-to-earth response on general information is what you will get.

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